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Aluminum (Al) is known as an important neurotoxic compound, the physiological action of Al is not known already, and in high concentrations can lead to intoxication and cause neurotoxicity

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Chen TR1977In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain.Exp

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This background suggests that the optimal condition for a drug to be more efficient in carrying out its therapeutic action would be to cross a BBB with good vascular integrity and without further damage in the neuronal functional state