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10.1038/s41581-020-00369-0 166 TangX.HuangM.JiangJ.LiangX.LiX.MengR.et al (2020)

Diabetes Care , 34 (7), 14811486

When reproducible physiology and biochemistry persist across years, modalities, and care settings, the question stops being is anything wrong? and becomes a governance one: Who owns the trigger for reevaluation when signals persist but dont fit a textbook pathway and where is that ownership documented so cases dont stall between handoffs

Deficiency Insufficient selenium intake may negatively affect the activity of several selenium-responsive enzymes, including glutathione peroxidases (specifically, GPx1 and GPx3), iodothyronine deiodinases, selenoprotein W, and methionine-R-sulfoxide reductase B1 (MsrB1)

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We understand, however, that potential patients often have questions regarding the cost of this treatment