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In the mitochondrial matrix, pyruvate dehydrogenase (PDH) generates acetyl-CoA using pyruvate, which initiates the TCA cycle, thereby producing reducing agents from carbohydrates (Figure 1)

doi: 10.1155/2016/3286365 [DOI] [PMC free article] [PubMed] [Google Scholar] 32.Kantah M, Kumari A, He F, Sollano J, Alagozlu H, Min CH, et al

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Specifically, 1-MNA regulates the immune system in ovarian cancers (113)