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In summary, while glutamatergic excitotoxicity via NMDA receptors is a well-supported mechanism in tinnitus, the clinical application of broad antagonists has been limited

High-dose vitamin C exerts its anti-cancer effects in a xenograft model of colon cancer by suppressing angiogenesis

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Cells were then harvested and resuspended in lysis buffer (40 mM Tris-Cl, pH 8.0, 400 mM NaCl, 5 mM 2-mercaptoethanol) and lyzed by sonication