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2.2 Lactate shuttle Lactate, the terminal glycolytic metabolite, functions as a versatile molecular shuttleintracellularly, intercellularly, and systemicallymodulating cellular bioenergetics and redox equilibrium while accumulating across tissues via circulatory transport ( The aforementioned glycolytic reprogramming drives profound lactate and proton accumulation

On la trouve notamment dans le foie, les lgumineuses (haricots mungo, lentilles), les herbes aromatiques (basilic, romarin, thym, etc.), les pinards et certaines crales (quinoa, muesli)

GPX4 immunoreactivity was visible in most TH-positive cells expressing neuromelanin, although expression levels varied from cell to cell

When that NNMT machine runs hot, especially in adipose tissue, it chews through SAM and eats into the raw material for NAD+

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These factors may compensate for the lack of peroxidase (Cramer et al., 1982)