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SUBLOCADE forms a solid mass upon contact with body fluids and may cause occlusion, local tissue damage, and thrombo-embolic events, including life threatening pulmonary emboli, if administered intravenously

doi: 10.3389/fmicb.2018.01652

Involvement of alcohol and aldehyde dehydrogenase activities on hepatic retinoid metabolism and its possible participation in the progression of rat liver regeneration

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In the context of nanomaterials, factors such as particle size, dosage regimen, administration route, surface chemistry, degree of aggregation, transmembrane diffusivity, excretion mechanisms, and immunogenic potential are the key determinants of nanotoxicity

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