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Physiology 6, 20

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First isolated by Dr

cGMP acts as a crucial intracellular second messenger influencing various pathophysiological processes

This crosstalk amplifies neuroinflammatory signaling and alters neurovascular integrity, contributing to blood-brain barrier disruption, glial priming, and neuronal injury 11-12

[13] [15] Rare but serious side effects include hypersensitivity reactions, such as urticaria, angioedema, or anaphylaxis, which require immediate medical attention