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The pathogenesis of diabetic cataract In diabetic patients, prolonged hyperglycemia leads to excessive accumulation of sorbitol in the lens, increased osmotic pressure, influx of aqueous humor, leading to intracellular edema and fiber breakage, ultimately leading to lens turbidity and further worsening the extent of oxidative stress

Small 18 , e2103868 (2022)

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These compounds target various molecular pathways involved in ferroptosis, including lipid peroxidation, iron metabolism, and antioxidant defense