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DECLARATIONS Authors contributions Developed the model, ran simulations and analyses, interpreted the findings, and contributed to the writing and editing of the manuscript: Cruikshank A, Reed MC, Nijhout HF Availability of data and materials Computer models and codes used in this paper can be obtained from the authors by request

A., Hiam D

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Its about deep health signals: - Sleep fragmentation - Elevated insulin and cortisol - Sedentary behavior - Artificial light at night - Chronic under-eating or over-restricting carbs and proteins - Shallow breathing, low VO2max, and poor mitochondrial turnover All of these suppress endogenous GH pulses, regardless of chronological age

doi: 10.3390/nu9111176