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10.1016/B978-0-12-407697-6.00002-7 135

GhFSN1 positively regulates the formation of cotton fiber SCWs by regulating the expression of its downstream genes GhIRX12 , GhMYB1 , GhGUT1 , and GhDUF231L1

N-acetyl cysteine was able to prevent acute kidney injury (acute renal failure) as documented by reduced biomarkers of oxidative stress and inflammation and increased antioxidant biomarkers (Ozturk et al

Key readout endpoints include serum ALT and AST enzyme release (hepatocyte membrane integrity), hepatic malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) as lipid peroxidation markers, H&E-stained hepatic necrosis area scoring (zones IIII centrilobular pattern), TUNEL-positive hepatocyte apoptosis count, and MPO activity as a proxy for neutrophil infiltration