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Only six cases of dihydrofolate reductase deficiency have been reported to date, three of which were homozygous mutations in the DHFR gene p.Asp153Val and three were attributed to p.Leu80Phe mutations [116, 117]

Furthermore, the usage of BP (high amount) in frankfurters can increase its oxidative stability and shelf life during chilled storage which is attractive to potential market consumers (105)

Several studies have shown low- to moderately-elevated PCT levels also among critically-ill patients without evidence of infection (trauma, major surgery, multi-organ failure and myocardial infarction) 2,3

under hypoxic conditions associated with testicular IR, excessive ROS results in oxidative stress 54

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Moreover, anti-angiogenic therapy can increase the effective concentrations of ADC drugs within tumors by inhibiting the expression of ABC transport proteins