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Front Pharmacol (2022) 13:806470

It emphasises gene interpretation and differential gene expression analysis (DGE), which is always its standard research tool, suitable for gene expression difference studies and pathway analysis of entire tissues or cell populations 12,13

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Moreover, glutamine is an important source of amide nitrogen for nucleotide synthesis, and it contributes to the activation of the mTORC1 pathway which promotes mTORC1-dependant metabolic reprogramming, increasing the proliferation and growth of tumors [36-40]

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