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Expanding adipose depots develop localized hypoxia that activates hypoxia-inducible factor 1- (HIF-1)-dependent signaling cascades, establishing self-perpetuating cycles of matrix accumulation

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Inducing the expression of HIF-1 through increasing the expression of fatty acid-binding proteins 3 and 7 under hypoxic conditions inhibits ferroptosis [108]

Mol Interv 7:31324 Mieyal JJ, Gallogly MM, Qanungo S, Sabens EA, Shelton MD (2008) Molecular mechanisms and clinical implications of reversible protein S -glutathionylation

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