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Niacinamide (optional) Helps to reduce blemishes and control oil

doi: 10.1002/anie.202300379 66 LiJCaoFYinHLHuangZJLinZTMaoNet al

Diehn M, Cho RW, Lobo NA, Kalisky T, Dorie MJ, Kulp AN, et al

IB is phosphorylated and degraded in response to pro-inflammatory stimuli (such as LPS and cytokines), which permits NF-B to go into the nucleus and stimulate the production of pro-inflammatory genes, such as TNF-, IL-6, and COX-2