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The role of early life nutrition in the establishment of gastrointestinal microbial composition and function

Cells dosed with a serial dilution of BSO showed no cytotoxicity compared to the vehicle control, indicating that the compound did not kill the cells (Figure 5, Panel A)

The PINK1/Parkin pathway is the most extensively studied mechanism of mitophagy, and comprises three main components: PINK1 as the mitochondrial damage sensor, Parkin as the signal amplifier and ubiquitin chains as the signal effectors (39)

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Renal I/R injury is widespread in clinical practice, commonly observed in conditions such as shock, trauma, renal transplantation, urology, and cardiovascular surgery, and can lead to a rapid decline in kidney function and increase patient mortality