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10.1016/j.aca.2019.10.031 218 ZhangQ.LiuQ.DuM.VermorkenA.CuiY.ZhangL.et al (2019)

Abstract Myogenic stem cell activator HGF (hepatocyte growth factor) undergoes nitration of tyrosine residues (Y198, Y250) predominantly on fast-twitch fibers to lose its binding affinity to the signaling receptor c-met, in response to peroxynitrite (ONOO - ) generation during aging

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This action reduces insulin resistance and helps regulate blood glucose levels, potentially mitigating hyperglycemia that contributes to nerve damage in DPN [39,69,85]