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Acyl-CoA synthetase long-chain family member 4 is considered a key ferroptosis-related enzyme, whereas LOX proteins have been identified as targets of ferroptosis inducers

Collectively, these findings represent the first biomarker/molecular difference that has been found to be different between children affected with konzo as compared to unaffected individuals and may serve as a biomarker for not only disease, but to identify children that harbor increased risk for disease susceptibility and severity

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Wu F, Lu R, Liu Y, et al

In theory, combining them could offer complementary benefits