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A central domain that forms the fibers in mature collagen has a characteristic amino acid sequence containing Gly-Xaa-Yaa repeats, where Xaa and Yaa could be any kind of amino acids [16]

In this regard, primary liver cell models may be more predictive, as they can cover not only phase I but also phase II metabolism, and thus possible deactivation of certain NAs (Madle et al

Ratha J, Majumdar KN, Dhara K, Singh SK, Saha KD, Bhadra R

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Results: We observed deficits in organoid structure and impaired neurogenesis in DTG-treated organoids compared to vehicle-treated control organoids after 20 or 40 days in culture