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Enrollment was halted for futility at a prespecified interim analysis as all 10 treated patients experienced rapid disease progression

Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart

CAS: 62568-57-4

The glass-bottom dish with the explants were treated with 1 M of Flipper-TR (CY-SC020) for 5 min in the microscopes imaging chamber set at 37 C and 5% CO 2

While these studies highlight the neuroprotective potential of CQDs in controlled assays, HEWL is a model protein with limited structural homology to disease-relevant aggregates, and the in vitro assays do not fully reflect neuronal environments

Appl Physiol Nutr Metab 32(6):11241131 Gomez-Cabrera MC, Via J, Ji LL (2009) Interplay of oxidants and antioxidants during exercise: implications for muscle health