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5-amino-1MQ is a small-molecule NNMT inhibitor developed in academic research labs and tested extensively in rodent models for obesity and metabolic disease

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The mechanism is simple L-carnitine shuttles long-chain fatty acids into mitochondria, where they are oxidized for energy

Dietary deficiency of copper is seen as lowered red cell copper and SOD, even in early stages of copper depletion

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*Correspondence: Suqing Wang [email protected] This article was submitted to Nutritional Epidemiology, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers