Who Should NOT Consider Peptides Based on current evidence, I would advise against peptide use in the following individuals: Anyone with a current or recent cancer diagnosis Anyone with a strong family history of hormone-sensitive cancers (breast, ovarian, uterine, prostate, colorectal) Anyone with genetic mutations predisposing to cancer (BRCA1/2, Lynch syndrome, etc.) Anyone with active autoimmune disease or severe inflammatory conditions Pregnant or breastfeeding women Anyone who has not established foundational health practices Competitive athletes (most peptides are banned substances) Anyone seeking a "quick fix" rather than commitment to comprehensive health optimization If Considering Peptides: A Cautious Approach For patients who have established solid foundations, have no contraindications, understand the limitations of current evidence, and wish to explore peptides as a potential adjunct, here is the approach I might considerwith significant caveats: Lower-Risk Starting Point Topical GHK-Cu: This has the most established safety profile and documented benefits for skin health
Diet and Lifestyle Advice Eat a Balanced Diet: Include fruits, vegetables, whole grains, and protein-rich foods
C15:0, the ingredient in fatty15, is GRAS (generally regarded as safe) certified, which means fatty15 is safe for children age 4+, pregnant women, nursing moms, and pretty much everyone except for infants and toddlers
Eur J Clin Invest 2011
doi: 10.1111/j.1447-0756.2010.01303.x
You'll find it in a wide range of products from shampoos to face cleansers
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