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Visual Characteristics of Lyophilized BPC-157 Depending on manufacturing conditions and freeze-drying parameters, lyophilized BPC-157 may appear as: Fine white powder Porous lyophilized cake Compact peptide puck adhered to the vial surface Minor variations between vials are normal and generally reflect differences in freeze-drying parameters, formulation composition, or vial geometry during manufacturing

T., van Marion-Kievit, J

37 KaiyaH.Van Der GeytenS.KojimaM.HosodaH.KitajimaY.MatsumotoM.et al

American Journal of Physiology-Gastrointestinal and Liver Physiology

In another aspect, the present invention broadly consists in a method of making a compound of the formula (XX), the method comprising reacting a compound of the formula (XXI): an amino acid-comprising conjugation partner comprising a thiol of the formula (III): under conditions effective to conjugate the compound of formula (XXI) and amino acid-comprising conjugation partner and provide the compound of formula (XX): Rm and Rn are each independently hydrogen, C1-6alkyl, aryl, or heteroaryl