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The presence of carbonyl compounds, such as formaldehyde, in e-cigarette aerosols results from the heated degradation of e-liquid components (e.g., propylene glycol and glycerin) and depends on device features (e.g., closed vs open systems) and device settings (e.g., heating temperature and voltage) and result in higher HPHC levels in e-cigarette aerosols from some devices [11, 56,57,58,59]

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Participants were considered to have bronchitic symptoms if they reported any of the following: bronchitis in the previous 12 months

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