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Transcription factors act as key regulatory nodes, integrating upstream signals with downstream responses: DREB/CBF proteins mediate ABA-independent pathways, whereas NAC, MYB, WRKY, and bZIP families regulate ABA-dependent networks controlling aquaporins, osmoprotective metabolism, and antioxidant capacity (Sornaraj et al

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It manifests by the failure to induce transcription of progesterone-target genes despite adequate hormonal bioavailability [36]

Jessup SK, Malow BA, Symons KV, Barkan AL

FIGURE 2 The structural hallmark of IDD is the progressive dehydration of the NP mainly due to the gradual loss of proteoglycans within the ECM (Vadal et al., 2015