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Note on humans: These benefits are not established in humans no completed clinical trials exist [1]

Interpreting trial results in real-world clinical practice Treatment effects reported in prescribing information may differ for the same product depending on the country/region and the preference of different regulatory agencies for reporting different analyses

To our knowledge, this is the largest study to date regarding the association of serum vitamin B12 levels with obesity in the general population

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What we can say with confidence is that the compounds target non-overlapping pathways, show no receptor competition in pharmacological models, and have individual safety profiles that don't predict catastrophic interaction