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Dosing: 300-600mg of root extract daily

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Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats

Adult retinal homogenates exposed to low BPA at 72 hpf had decreased p-ERK and p-Akt protein levels but increased p-JNK

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Chemically, ALA contains a dithiolane ring that can undergo reduction to dihydrolipoic acid (DHLA) in the body