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Increased exposure of anionic phospholipids on the surface of tumor blood vessels

For example, in glioblastoma models, engineered exosomes have successfully delivered chemotherapeutic agents with improved tumor targeting while sparing healthy tissues [12]

Therefore, NRF2 plays an important role in maintaining the cell redox balance and preventing ferroptosis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 670.Hjortland GO, Garman-Vik SS, Juell S, Olsen OE, Hirschberg H, Fodstad O, et al

The TWEAK-Fn14 system is a critical regulator of denervation-induced skeletal muscle atrophy in mice