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Most improvements documented in trials were measured over weeks of continuous use, and any effect is expected to fade if you stop taking it

307 Renal metabolic mechanisms and diseases Emerging evidence increasingly supports the pathogenic role of hyperuricemia in both the onset and progression of chronic kidney disease (CKD)

Pregnancy and breastfeeding are the only female-specific contraindications

One isnt necessarily better than the other

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It is often found in earlier medicine research where concentrations tested on animal models are unattainable in the blood circulation of human patients, compromising physiological relevance