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While melatonin has been shown to be effective in various situations, it is essential to note that individual responses may vary

Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development

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84,85 These findings emphasize the significant involvement of different cytokines and the JAK/STAT pathway in the pathogenesis of CRS, indicating the potential efficacy of targeting the JAK/STAT pathway as a therapeutic approach for CRS