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Recognizing External Concerns and Self-Reflection: Awareness of AUD can arise through external concerns voiced by friends, family, or colleagues

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Why did dihexa never enter clinical trials if the animal data was promising? Pharmaceutical companies evaluate preclinical compounds based on risk-benefit calculus, intellectual property landscape, competitive market positioning, and probability of regulatory approval many promising animal compounds are abandoned before human trials because the investment required for Phase 13 studies (often $50$100 million) cannot be justified

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