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Corroborating our murine data, analysis of human HCC specimens confirmed that augmented mtDNA levels in TAMs are closely associated with immunosuppression and unfavorable patient prognoses

2OGDH, 2-oxoglutarate dehydrogenase

A previous study revealed that p-AKT can enter the nucleus and phosphorylate FOXO3A, which promotes the expression of genes necessary for PMF activation 29

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A cholesterol-conjugate with glucuronic acid has been isolated from human liver (33 nmol/g wet tissue) and plasma, but its origin, function and metabolic fate are unknown

These neurotrophins play a crucial role in the survival, repair, and regeneration of peripheral nerves, enhancing neuronal health and functional recovery [99,100,101]