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Notably, clinical trial involving the use of Daratumumab and Atezolizumab (anti-PDL1) (NCT03023423) was also halted due to the lack of clinical efficacy ( 5 Conclusions Despite the small sample size, this study has important clinical implications in the treatment of NKTL patients

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Table 15: Efficacy Results in PARAMOUNT Figure 8: Kaplan-Meier Curves for Overall Survival in PARAMOUNT Treatment of Recurrent Disease After Prior Chemotherapy The efficacy of pemetrexed for injection was evaluated in Study JMEI (NCT00004881), a multicenter, randomized (1:1), open-label study conducted in patients with Stage III or IV NSCLC that had recurred or progressed following one prior chemotherapy regimen for advanced disease

Furthermore, research indicates that high body iron stores in early pregnancy are also associated with an increased risk of developing GDM [102]

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SAR650984, a novel humanized CD38-targeting antibody, demonstrates potent antitumor activity in models of multiple myeloma and other CD38+ hematologic Malignancies