glutathione is an antioxidant Oral delivery of glutathione: function, barriers and strategies – ScienceOpen Glutathione & Vitamin C IV

Furthermore, progressive loss of NRF2 activity was seen with aging, which may be explained by studies showing that the expression of NRF2 positive regulators P62 and BRCA1 decreased with age, while NRF2 negative regulators, KEAP1 and BACH1, increased with age [113]

Artesunate attenuates lung injury in paraquat-intoxicated rats via downregulation of inflammatory cytokines

Flecknell, P

Kitabayashi C, Fukada T, Kanamoto M, Ohashi W, Hojyo S, Atsumi T, et al

The level of ALT and AST, a major marker of hepatic damage in the serum, highly elevated in the liver of WT mice with Con A administration but not in the liver of Gpx1 KO mice with Con A administration

doi: 10.1016/S0140-6736(19)32563-2 37 SantosR