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The mediator concentrations used in these studies were selected based on initial measurements that served to tune conditions to obtain useful output signals

10.1002/hep.31288 107 MeierJ

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n = 3 independent experiments)

It forms a complex with cyclophilin, a cytoplasmic protein present in T-cells, that inhibits the activity of calcineurin, a calcium/calmodulin-dependent phosphatase

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