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GPX4 knockdown by siRNA N1IC or P53 cells were plated in poly-L-lysine-coated 24-well plates (6.2 10 4 cells/well) for 18 h in BFP media with or without 2 M Ferrostatin

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The diquat-treated rats were treated with 0.0750.25 mmol/kg of diquat, while the control group only received normal saline via IP injection