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Description

Vanheel et al., 2014)

368,369,370 HSF2 and DLG2 can block the oligomerization of ASC by interfering with the interaction between ASC and NLRP3, thereby inhibiting the activation of the NLRP3 inflammasome and the upregulation of IL-1 expression and alleviating the inflammatory response

GHK-Cu works through gene expression modulation

Topical effects Most reported topical effects are mild and local: redness, tingling, dryness, or transient irritation at the application site, typically more common with concentrations above 4%