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Primary Research Areas NNMT enzymology and pharmacology the lead first-in-class selective small-molecule NNMT inhibitor used to validate the entire target class [1,2]
Its not just one result but a series of clues that, when put together, tell a story
This takes in the entire med history, medication and allergy check, and reviews for pregnancy or breastfeeding
The common drivers: A weak or loose LES A hiatal hernia (part of the stomach pushing up through the diaphragm) Eating large meals, especially within three hours of bed Excess abdominal weight pressing on the stomach Smoking (which relaxes the LES) Pregnancy Certain medications, including some blood pressure drugs and asthma inhalers I tell patients this all the time: if you have reflux and youve never had a proper workup, youre treating a symptom and ignoring the engine
