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291 In the absence of TSC2, hyperactivated mTORC1 phosphorylates S6K1 and inactivates GSK3, leading to the dephosphorylation and activation of glycogen synthase, which promotes glycogen synthesis

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Multi-immunometabolomics mining: NP prevents hyperimmune in ALI by inhibiting Leucine/PI3K/Akt/mTOR signaling pathway

These factors disrupt intercellular communication within the corpus cavernosum and reduce nitric oxide (NO) bioavailability, thereby exacerbating endothelial dysfunction and ultimately impairing erectile function[65]

The search subject terms included diabetic kidney disease, Traditional Chinese Medicine, mTOR, nutrient sensing, and oxidative stress. Studies were rigorously screened by two investigators

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