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The harmful chemicals in tobacco smoke can reach different parts of the body through the bloodstream, increasing the likelihood of cancer development in these areas

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Preacher KJ (2015) Advances in mediation analysis: a survey and synthesis of new developments

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were reported currently smoking combustible cigarettes, with more than 16 million Americans living with a smoking-related disease

Causes of Salivary Gland Cancer The exact causes of salivary gland cancer are still not fully understood, but several risk factors have been identified: Exposure to radiation (medical treatments or environmental) Older age Family history of salivary gland or other head and neck cancers Long-term exposure to chemicals or dust in workplaces Smoking (especially linked to some rare types) Although these factors can increase the risk, some people with salivary gland cancer have no known risk factors