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Still, its not clear whether B12 supplementation can reduce the risk of heart disease directly (13)

TETM vs

Haemoglobin levels begin to rise after about one week, whilst the mean corpuscular volume (MCV), which is typically elevated in B12 deficiency, gradually normalises

[In a previous post on Conjugation and Resonance we mentioned that this manifests itself as a barrier to rotation in the C-N bond of about 15-20 kcal/mol ] 3