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Gastrointestinal side effects (nausea, vomiting, diarrhea, constipation) are common and dose-dependent

Studies have indeed demonstrated that hyperhomocysteinemia compromises microvascular function in various organs, including the microvascular system within the kidneys [60]

The HPLC solvents were: solvent A, 1.5% v/v ortho-phosphoric acid (EMP Chemicals, Gibbstown, NJ), and solvent B, consisting of 80% acetonitrile (HPLC grade, Honeywell, Muskegon, MI) with 20% of solvent A

C., Betson, M

Best Practice in the chemical characterisation of extracts used in pharmacological and toxicological research-The ConPhyMP-Guidelines

Lin CY, Trinh NN, Fu SF, Hsiung YC, Chia LC, Lin CW, Huang HJ (2013) Comparison of early transcriptome responses to copper and cadmium in rice roots