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Restraining Akt1 phosphorylation attenuates the repair of radiation-induced DNA double-strand breaks and reduces the survival of irradiated cancer cells

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Interestingly, in SOD1 G93A ALS mice there was massive infiltration of CD4 + and CD8 + T-cells in the spinal cord just following the onset of symptoms [30, 143], indicating that T-lymphocytes are involved in earlier disease events