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Symptoms typically include: Facial pain or pressure Blocked or stuffy nose Thick mucus discharge Headaches, particularly when leaning forward Ear pain or pressure Reduced sense of smell In many cases, sinus infections clear up on their own, but sometimes the symptoms persist and require treatment to relieve the discomfort and speed up recovery

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Although, it is an attractive anti-obesity and anti-diabetes target, FGF21 levels are increased in obese ob/ob and db/db mice and correlate positively with BMI in humans