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One key concern is safety, particularly the potential for malignant transformation of cells used in cellular based therapies

FIGURE 7 Functional Annotation Study of PavGST Genes Gene ontology (GO) enrichment was evaluated in the biological process, subcellular localization, molecular function, and cellular components, which was beneficial for understanding protein function at the molecular level

Shen Y, Li L, Grant J, Zhao Z, Zhang X, Zhou L, Fowler D: Anaphylactic deaths in Maryland (US) and Shanghai: a review of forensic autopsy cases from 2004 to 2006

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Conclusion ATC shows many GA with potential therapeutic significance and suggesting different molecular pathways can lead to ATC