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Paeonol (Pae) upregulates FOXO3 by inhibiting the expression of miR-155, thereby preventing the proliferation induced by TNF- and the release of cytokines in RAM model, with weakened the generation of IL-6 and IL-1 (64)

Most antibiotics cannot do that

Plant roots grown in vitro have low water conductivity and weak root-stem connections, making water uptake challenging

Key signaling pathways, including peroxisome proliferator-activated receptor (PPAR) and Notch, regulate FABP4 expression to facilitate transendothelial FA transport [84, 85]

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Beyene Department of Microbiology, Addis Ababa University, Addis Ababa, Ethiopia Habtamu B