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It was historically used in human medicine but is now primarily used in veterinary medicine, particularly for horses, to promote muscle growth, improve nitrogen balance, and enhance appetite

257,259 Moreover, JAK3 mutations have been shown to lead to severe immunodeficiencies, whereas STAT3 mutations impair IL-17 production, which increases susceptibility to bacterial and fungal infections

The gap between BPC-157's animal research profile and its human evidence base has long been striking

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Hence, poor quality sleep over time has been associated with a risk of developing neurodegenerative diseases (Valverde et al., 2022)

Hambright et al., 2017