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Studies have reported OCTN2 expression in respiratory epithelial cells and alveolar macrophages, which is especially high in the upper lung region [301], and OCTN2-mediated carnitine uptake plays an important role in maintaining respiratory cilia beating and airway mucociliary clearance function, helping to remove excess mucus and potentially harmful substances from the airway [302]

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Researchers curious about how the amylin pathway is discussed alongside a dual GIP/GLP-1 agonist can read our guide to cagrilintide dosage with tirzepatide

This pricing gap largely reflects tirzepatide being a newer medication with a dual-agonist patent, whereas semaglutide is a more established drug with potential generics on the horizon around 2028