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These effects of zinc on -glucuronidase and UGT can explain the paradoxical association of anosmia with zinc deficiency (Pisano and Hilas 2016) and high-zinc resulting from the intranasal administration of zinc solutions (Alexander and Davidson 2006)

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This activation results in the induction of an array of cytoprotective genes, such as those of NAD(P)H quinone dehydrogenase 1 (NQO1), heme oxygenase 1 (HO1), GPx, GR, and SOD (54, 55)