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Because it is a peptide naturally present in the human body, it is thought to be well tolerated at low concentrations

Shedding can also rise after fever, surgery, major stress, or rapid weight loss, and that pattern is often called telogen effluvium

10.1146/annurev-immunol-042617-053119 27 PrataL

Younger users with less accumulated damage may notice changes sooner, while older users with more significant collagen loss may need the full 12+ weeks before results become clearly visible

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