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10.1016/J.FREERADBIOMED.2010.02.024 138 OgawaK.SunJ.TaketaniS.NakajimaO.NishitaniC.SassaS.et al (2001)

PLoS One 7, e43249

34 Furthermore, recent studies from Stuart Franks laboratory have shown that the GHR and prolactin receptor form complex heteromultimeric structures that may affect GH signal transduction in some cell lines

When examined together, the peptides may demonstrate intersecting pathways that researchers suggest could represent synchronized receptor activation

The Dual Agonist Breakthrough: Why Two Is Better Than One Tirzepatide, the first dual GLP-1/GIP agonist to reach market, demonstrated that activating both receptors produces superior results to activating GLP-1 alone

found that the expression of Prdx6 was regulated by specificity protein 1 (Sp1) at the transcriptional level, and the upregulation of Prdx6 could prevent podocyte impairment in DKD by alleviating oxidative stress and ferroptosis[84]